Vaccine Drug Substance Development Scientist (H/F)

About the job As Vaccine Drug Substance Development Scientist VIE within our CMC (Chemistry, manufacturing and controls) Development team, you will have the opportunity to develop the ability to lead and function creatively within a team, while maintaining attention to strict compliance. You will acquire knowledge of industry constraints and regulations. The Vaccine Drug Substance Development (VDSD) within the Global Bioprocess Development (GBD) department actively supports process development of novel vaccine candidates utilizing techniques such as viral cell culture, bacterial fermentation, molecular biology, downstream processing (chromatography, TFF) and supportive analytical techniques. We develop and scale up upstream and downstream processes for new vaccines up to 200L scale. Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization. Ready to get started? About Sanofi We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. Main responsibilities: - Phase I and II drug substance process development for recombinant protein vaccine candidates. - Plan and execute upstream process optimization and scale-up studies using technologies such as AMBR high-throughput bioreactor system, small and pilot scale bioreactors. - Plan and execute midstream and downstream process optimization and scale-up studies using technologies such as TECAN high-throughput chromatography screening, AKTAs, Tangential Flow Filtration (TFF) and various filtration methods. - Supportive analytical testing including viral titration assays, Flow cytometry, protein assays, Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis (SDS-PAGE), Western blot, High-Performance Liquid Chromatography (HPLC), Limulus Amebocyte Lysate (LAL) and others. - Statistical data analysis, preparation of technical reports and stakeholder presentations. - Planning, execution and statistical analysis of Design of Experiment studies. - Tech transfer of processes to Global Clinical manufacturing team or Manufacturing Science and Technology (MSAT). - Contribute to Sanofi’s digital and automation initiatives. Why choose us? - Be part of a pioneering biopharma company where patient insights shape drug development. - Work at the forefront of AI-powered science that accelerates discovery and improves outcomes. - Collaborate beyond your expertise, sparking new ideas with diverse, multidisciplinary teams. - Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science. - Help improve the lives of millions of people globally by making drug development quicker and more effective. - Join a workplace where diversity, equity, and inclusion are at the core, with Employee Resource Groups and leadership programs that celebrate every voice. iMove is a unique program tailored for European youth interested in challenging themselves with meaningful assignments across the globe. At Sanofi we have a strong ambition to invest in young talents who will drive the success of Sanofi tomorrow. Sanofi’s Work Abroad Program, iMove, offers jobs-assignments with actual responsibilities and a perspective to grow. We provide those opportunities in various functions such as: marketing, finance, regulatory, supply chain, clinical trials, production, etc. and in more than 40 countries. Sanofi unites people who are passionate about solving healthcare needs across the world. Joining our iMove Work Abroad Program is a unique opportunity to make a difference through your work. Pursue Progress. Discover Extraordinary. Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together. At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity. Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

About you Experience: - Knowledge and experience with bioprocessing methods and process scale-up. - Demonstrated experience with mammalian cell culture and downstream processing. - Experience in analytical techniques such as titration assays, flow cytometry, protein assays (BCA), SDS-PAGE, Western blot, HPLC would be an asset. Soft and Technical skills: - Mandatory Computer skills: Word, Excel, PowerPoint. - Expertise in Statistical analysis and software (JMP, GraphPad Prism) would be an asset. -Leadership skills. - Demonstrate accountability and motivation. - Strong attention to detail and analytical skills. - Excellent communication and interpersonal skills. - Desire to work within a team environment. Education: - Master’s degree in Biochemical Engineering / Life Sciences / Biology / Immunology / Biochemistry disciplines. Languages: - Fluent English (written and verbal). To facilitate the examination of your application by our English-speaking managers, thank you for applying in English.

La volonté de faire progresser la science nous unit. En France, nous sommes plus de 20 000 hommes et femmes passionnés. L’innovation est un parcours inattendu de défis. Alors, sans relâche, nous repoussons nos limites pour transformer la pratique de la médecine et améliorer la santé des patients avec nos médicaments et vaccins.